According to a recent paper published the Lancet, a superbug gene that confers resistance to colistin, an antibiotic used to treat Gram-negative bacterial infections when all other drugs fail, has been discovered in China (Liu et al., 2016; TheStar, 2016). The gene in question, called MCR-1, was found in E.coli in samples from meat, hospital patients, and livestock in southeastern China. Given that China is among the countries with the highest colistin use in agriculture, resistance to the drug may have originated in that part of the world; however, new reports show that the gene is not restricted to China as the following countries have similarly discovered MCR-1 in bacterial DNA: Algeria, Canada, Denmark, England, France, Laos, Portugal, Thailand, The Netherlands, and Wales (TheStar, 2016). Some of the bacterial DNA analyzed and found positive for the MCR-1 gene was derived from specimens archived before 2015; therefore, dissemination of the gene has outpaced discovery, and the issue at hand may already be an international crisis.
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